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KMID : 0386719940060020210
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Journal of the Korean Hip Society
1994 Volume.6 No. 2 p.210 ~ p.217
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Bone Resorption Activity of the Interface Membrane from Loosened THA
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장재석
김기용/이수호/정종기/이석현
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Abstract
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We have isolated cels from the interface membrane between bone and implant to identify which cell was platying a role in the bone resorption. The interface membrane was made up of three layers of which foreign bodies and
granulomas
were identified and the foreign bodies were confirmed mostly to be the polyethylene by the polarized microsope.
The morpholohy of the cultivated cells were variable; mononuclear cells were spindle or polygonal shape and giant cells were also identified. The giant tells were positive to TRAP reaction and negative to immunocytochemistry to CD 11b
and
CD
14 which shows same phenotype expression with osteoclasts. And they could make resorption pits on cacified bine slices.
We have confirmed the bone resorption activity of the giant cells of interface membrane of which activity would persist as long they exist, so adequate implant material and operative techniques are needed to eliminate these
bone-implant
interface membrane.
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KEYWORD
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